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Organ transplants from pigs may be viable in the future

Organ transplants from pigs may be viable in the future
Aug 16, 2017
By Kaitlynn Anderson

CRISPR technology allowed researchers to eliminate interfering viruses

By Kaitlynn Anderson

Farms.com

 

Pork producers may be excited to learn that there could be a new market for pigs in the future.

The reason? Transplants.

Researchers at eGenesis, a start-up in Massachusetts, have discovered a way to inactivate 25 viruses in the pig genome. Previously, the threat of viruses had been one of the obstacles that prevented organ transplants to humans from being viable. These retroviruses may induce tumors and immunodeficiencies, according to a 2012 article in Clinical Microbiology Reviews.

Using the CRISPR-Cas9 system, the researchers produced healthy piglets, according to an article in the Scientific American. At the age of four months – the age at which the animal’s organs are large enough to be used for transplants – the pigs were still healthy.

Next, the researchers plan to further modify the animal’s organs so that they can function in the human body.

This modification will involve making the pig tissues compatible with humans, eliminating blood-clot issues and carrying out some changes to the immune system, according to George Church, co-founder of eGenesis and Harvard Medical School geneticist.

 


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Guardians of Swine Health - Unveiling the PRRS/PEDV Enigma with Dr. Gisele from Lanxess

Video: Guardians of Swine Health - Unveiling the PRRS/PEDV Enigma with Dr. Gisele from Lanxess

Welcome to a riveting episode of "Guardians of Swine Health," where we embark on a journey through the intricate tapestry of swine health. Joining us today is the esteemed Dr. Gisele from Lanxess, a beacon in the field of biosecurity. Together, we delve into the enigma of PRRS and PEDV, unraveling the complexities that challenge swine herds worldwide. Exploring the Viral Enigma: Dr. Gisele takes center stage, guiding us through a captivating PowerPoint presentation. She unravels the mysteries surrounding PRRS and PEDV, shedding light on the pathogens that threaten the respiratory, reproductive, and digestive systems of our beloved swine populations. Focus on Critical Gaps: Our exploration zeroes in on the critical gaps that persist during disinfection and cleaning practices. Dr. Gisele, with her wealth of expertise, navigates us through the nuances of biosecurity, emphasizing the need for a holistic approach in safeguarding swine herds. Cost Savings through Strategic Biosecurity: The presentation takes an insightful turn as Dr. Gisele unveils the economic impact of strategic biosecurity measures. She demonstrates how a robust approach not only protects swine health but also translates into substantial cost savings for farmers. It's a win-win for both the pigs and the pocketbook.

Key Points:

1. Understanding PRRS and PEDV:

o Dr. Gisele provides a comprehensive overview of the PRRS and PEDV pathogens, ensuring a deep understanding of the threats faced by swine herds.

2. Navigating Biosecurity Gaps:

o The discussion explores the critical gaps in current disinfection and cleaning practices, offering insights on how to fortify these weak points.

3. Cost-Effective Strategies:

o Dr. Gisele unveils actionable strategies that not only enhance swine health but also contribute to significant cost savings for farmers.

Conclusion: As Dr. Gisele concludes her presentation, we're left with a profound appreciation for the intricate dance between science and practicality in swine health. This episode serves as a beacon for farmers, veterinarians, and enthusiasts alike, guiding them in the relentless pursuit of safeguarding our swine herds against the enigmatic threats of PRRS and PEDV.
 

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