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Abstract: Distribution of Coronavirus Receptors in the Swine Respiratory and Intestinal Tract

Abstract: Distribution of Coronavirus Receptors in the Swine Respiratory and Intestinal Tract

Coronaviruses use a broad range of host receptors for binding and cell entry, essential steps in establishing viral infections. This pilot study evaluated the overall distribution of angiotensin-converting enzyme 2 (ACE2), aminopeptidase N (APN), carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1), and dipeptidyl peptidase 4 (DPP4) receptors in the pig respiratory and intestinal tract. All the receptors evaluated in this study were expressed and differentially distributed through the respiratory and intestinal tract. The presence and expression levels of these receptors could determine susceptibility to coronavirus infections. This study may have important implications for the development of research models and the assessment of the potential risk and introduction of novel coronaviruses into the swine population.

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Selling Rams & Helping New Farmers Begin

Video: Selling Rams & Helping New Farmers Begin

It’s shipping day again at Ewetopia Farms as we sell another Suffolk yearling ram! In today’s episode, we load one of our Suffolk rams onto the trailer as he heads off to his new farm to sire the next generation of lambs.

This particular customer has been buying our rams for over eight years, trusting Ewetopia genetics for their gentle temperaments, strong builds, and proven performance. Back home, we get busy looking after the flock that’s staying behind. With the weather turning wet and chilly, it’s time to put down fresh, clean bedding to keep everyone cozy and comfortable for the season ahead. Later, we welcome a wonderful new family who’s just starting out in sheep farming!

They’ve chosen some of our Suffolk ewe lambs to begin their flock — and we couldn’t be happier to help them take their first steps into raising sheep. Stay tuned for a follow-up episode when we help deliver and settle their new flock at their farm.