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Increase production profitability through a more efficient nutrient uptake

Using a nutrient absorption enhancer like Lysoforte Extend can support piglet performance by increasing feed efficiency and the incidence and severity of post-weaning diarrhoea.

The post weaning period for piglets has always been challenging, with variable performance often observed as young piglets adapt to life away from the sow. The rapid change in diet and environment comes at a time when the piglet’s digestive system is still immature and producing far lower levels of gastric enzymes than its adult counterpart. Hence, the ability of piglets to optimally digest nutrients is still insufficient, leading to undigested substrate in the hindgut that causes proliferation of pathogenic bacteria and subsequent diarrhoea.

Stress and poor digestibility
The combination of environmental and physiological stress can be self-perpetuating, with diarrhoea further reducing nutrient absorption and poorer digestibility leading to even more undigested substrate in the hindgut. It is therefore not surprising that performance can be highly variable after weaning, which may increase the number of days required to produce piglets large enough to move on to the grower phase, in addition to the quantity of feed required for it.

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Porcine Gut Models in Nutrition Research - Dr. Li-Hsuan Chen

Video: Porcine Gut Models in Nutrition Research - Dr. Li-Hsuan Chen



In this episode of The Swine Nutrition Blackbelt Podcast, Dr. Li-Hsuan Chen, postdoc researcher at Aarhus University, discusses how porcine intestinal cell lines and organoids can help study the impact of nutrition on gut health. He explains how in vivo piglet trials identify diet-driven shifts in microbiota and metabolites, while in vitro models allow researchers to test specific metabolites, barrier function, immune markers, and future organ-on-chip systems before moving back to animal studies. Listen now on all major platforms!

"In vitro models can reduce early animal use by helping researchers screen nutritional candidates before moving back to in vivo trials."

Meet the guest: Dr. Li-Hsuan Chen / li-hsuan-chen-9a95a7279 is a postdoc researcher at Aarhus University in Denmark. Research focuses on porcine gut health, host-microbe interactions, cell lines, and organoids, with PhD work at Aarhus University studying how dietary protein and amino acid levels shape gut microbiota, microbial metabolites, and intestinal epithelial responses. Learn more from Dr. Li-Hsuan Chen on The Swine Nutrition Blackbelt Podcast, available on all major platforms.