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Genetic Audit of Wheat - Researchers Determine the Actual Variability of a Gene Responsible for Bread Quality

By Gaby Clark

A team at the University of Córdoba (UCO) has reviewed and updated the catalog of versions of the wheat gene GLU-B1, which is responsible for a protein that makes up gluten. The team has also made a collection of wheat representing the gene's true variability available to the research community.

Gluten gives bread its spongy crumb, makes pizza dough stretchy and keeps pasta from falling apart when cooked. Its viscoelastic protein network makes wheat special. Glutenins are among the proteins responsible for these properties of wheat flour dough, and wheat breeders have studied them for decades.

For more than 40 years, researchers have identified multiple variants (alleles) of the GLU-B1 gene, which encodes two high-molecular-weight glutenin subunits that are key to the quality of wheat-based products. The Catalogue of Gene Symbols for Wheat lists up to 98 alleles (different versions of the GLU-B1 gene). Until now, however, not all the alleles identified in wheat from around the world had been compared with one another.

Researchers from the Department of Genetics at the University of Córdoba—Francisco Andrade, Juan Bautista Álvarez and Carlos Guzmán—conducted a genetic review to check whether the reported variability was accurate or had been overestimated. "We collected wheats carrying these alleles from all over the world, studied their GLU-B1 variants, and compared them with each other," Guzmán said.

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