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Acidification Kills H5N1 in Waste Milk, Reducing Risk of Bird Flu

By Amy Quinton

Pasteurization is the only widely recognized method of killing H5N1, the virus that causes bird flu, in milk. However, pasteurization can be expensive and fewer than 50% of large dairy farms pasteurize waste milk.

Waste milk includes colostrum, the first milk after calving; milk from cows treated with antibiotics or other drugs; or any other factor that can make milk unsuitable and unsellable for human consumption. On farms, raw waste milk poses a potential risk of spreading avian flu, which so far has been confirmed in  in 16 states.

University of California, Davis, researchers have found that acidification can kill H5N1 in waste milk, providing  an affordable, easy-to-use alternative to  of waste milk. The Journal of Dairy Science published the study.

"There can be a quite significant cost to have pasteurization as an option on the farm," said co-corresponding author and veterinary epidemiologist Richard Van Vleck Pereira, with the UC Davis School of Veterinary Medicine. "In our , we found that acidifying milk to a pH of 4.1 to 4.2 with  effectively deactivates the virus."

The UC Davis research team will next conduct on-farm testing of milk acidification in waste milk containing H5N1. They will develop practical guidelines for farmers to implement acidification of waste milk as a protocol on the farm.

A sustainable solution

Pereira said citric acid is inexpensive. Acidified waste milk is also safe to be used to feed pre-weaned calves. The acidification process takes only six hours to fully kill the virus and doesn't require refrigeration, further reducing costs and increasing safety of farm workers handling milk.

Hobby farmers milking one or two cows or large commercial dairy farms could implement milk acidification without having to invest in large equipment.

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In this episode of The Swine Health Blackbelt Podcast, Dr. Talita Resende, Assistant Professor and Food Animal Diagnostician at the University of Minnesota Veterinary Diagnostic Laboratory, explains how sapovirus affects suckling and weaned pigs with diarrhea. She discusses PCR interpretation, rotavirus and E. coli coinfections, intestinal sampling, and in situ hybridization for clearer diagnostic decisions. Listen now on all major platforms!

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Meet the guest: Dr. Talita Resende / talita-resende-01188234 is an Assistant Professor and Food Animal Diagnostician at the University of Minnesota Veterinary Diagnostic Laboratory. Her work focuses on swine diseases, veterinary diagnostics, pathology, teaching, research, and service, with previous roles at The Ohio State University and universities in Brazil. Learn more from Dr. Talita Resende on The Swine Health Blackbelt Podcast, available on all major platforms.