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Leman Swine Conference: Vaccination strategies to reduce PRRS virus recombination

May 05, 2025

Video: Leman Swine Conference: Vaccination strategies to reduce PRRS virus recombination

Dr. Jay Calvert, Research Director with Zoetis, recently spoke to The Pig Site’s Sarah Mikesell at the 2023 Leman Swine Conference in St. Paul, Minnesota, USA, about his conference presentation on porcine reproductive and respiratory syndrome (PRRS) virus recombination.

“The number one problem in PRRS these days from a vaccine point of view is the emergence of new strains of PRRS. Since the beginning, we have had new strains and a lot of diversity,” said Dr. Jay Calvert. “We thought we knew it was all about mutation changes in amino acids and the individual strains over time, but they take on new characteristics.”

With the onset of more common whole genome sequencing and recombination analysis, Dr. Calvert says there is another mechanism, and recombination seems to be a key factor.

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