BASF Agricultural Solutions starts global registration of novel PPO herbicide Replexor™ Active

BASF Agricultural Solutions has begun the registration process for Replexor™ Active (fendioxypyracil), a novel herbicide active ingredient from its protoporphyrinogen oxidase (PPO) innovation pipeline with broad-spectrum activity on both broadleaf weeds and grasses. At peak adoption, Replexor Active could support weed management programs covering more than 50 million hectares globally. First regulatory dossiers are being submitted in Brazil and Australia in July 2026, with filings in the United States and Argentina planned for 2027. Pending approvals, BASF targets first market introductions of Replexor Active around 2030.

Herbicide-resistant weeds are a growing challenge for farmers of major crops such as soybean, corn, and cotton. At the same time, regulatory pressure is reducing the number of available active ingredients, further limiting effective control options.

In this context, PPO herbicides have been a reliable cornerstone of resistance management for more than 50 years. With Replexor Active, BASF extends that portfolio – which includes Kixor^® Active and Tirexor^® Active – with a new level of weed control. While most existing PPO herbicides primarily target broadleaf weeds, Replexor Active also controls key annual grasses such as Eleusine indica, Echinochloa spp., and Setaria spp. With PPO resistance in grasses remaining rare, Replexor Active adds a valuable new option for managing resistant grass weeds.