New EPA Herbicide Proposal Brings Added Requirements for Corn, Soybean and Wheat Acres

What Growers Should Know

• New burndown option under review — EPA is seeking public comment on epyrifenacil, a proposed pre-plant burndown herbicide for corn, soybean and wheat, plus fallow acres commonly used across Nebraska.

• No human health risks identified — EPA’s risk assessments found no human health concerns when used according to the label.

• Environmental mitigations likely — Proposed spray-drift buffers, runoff protections and rain/saturated-soil restrictions may influence how and when Nebraska growers can apply the product.

• Endangered species protections required — Application will require checking EPA’s “Bulletins Live Two” system for any local endangered-species restrictions before spraying.

• Public comment open — Growers, agronomists and crop advisors can provide input through Dec. 3, 2025, on how the proposal may affect field operations and weed-control planning in Nebraska.