$800,000 USDA Grant to Create Integrative Data Platform for Major Swine Diseases

Sep 18, 2023

A team of University of Minnesota College of Veterinary Medicine researchers led by Kimberly VanderWaal was recently awarded a 4-year, $800,000 Agriculture and Food Research Initiative (AFRI) grant from the United States Department of Agriculture (USDA) and the National Institute of Food and Agriculture (NIFA). The study aims to create an “integrative data science” platform to predict the ability of PRRSV-2 variants to provoke an immune response and spread across farms. The platform will use interconnected machine learning tools from structural biology, computational immunology, and genomic epidemiology.

The circulation of porcine reproductive and respiratory syndrome virus-type 2 (PRRSV-2) is a primary constraint to swine health and production. PRRSV-2 is a rapidly evolving RNA virus impacting roughly 30–50% of breeding farms. With an economic burden of over $600 million in the U.S. alone, PRRSV-2 is the most important endemic disease to the U.S. swine industry.

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Video: Intrauterine Vaccines in Swine - Dr. Heather Wilson

In this episode of The Swine it Podcast Show Canada, Dr. Heather Wilson from VIDO at the University of Saskatchewan explains how intrauterine vaccination is being developed as a new option for swine health. She shares how formulation, adjuvants, and delivery methods influence immune responses and what early trials reveal about safety and reproductive performance. Listen now on all major platforms.

"The idea was that an intrauterine vaccine might avoid a tolerance response and instead create an active immune response."

Meet the guest: Dr. Heather Wilson / heather-wilson-a8043641 is a Senior Scientist and Program Manager at the Vaccine and Infectious Disease Organization at the University of Saskatchewan. Her work centers on vaccine formulation and delivery in pigs, including the development of intrauterine vaccination to support reproductive health and passive protection of piglets. Her background spans biochemistry, immunology, and functional pathogenomics.