Effect of Antimicrobial Use in Agricultural Animals on Drugresistant Foodborne Campylobacteriosis in Humans: A Systematic Literature Review

Aug 12, 2016

Controversy continues concerning antimicrobial use in food animals and its relationship to drug-resistant infections in humans. We systematically reviewed published literature for evidence of a relationship between antimicrobial use in agricultural animals and drug-resistant foodborne campylobacteriosis in humans. Based on publications from the United States (U.S.), Canada and Denmark from 2010 to July 2014, 195 articles were retained for abstract review, 50 met study criteria for full article review with 36 retained for which data are presented. Two publications reported increase in macrolide resistance of Campylobacter coli isolated from feces of swine receiving macrolides in feed, and one of these described similar findings for tetracyclines and fluoroquinolones. A study in growing turkeys demonstrated increased macrolide resistance associated with therapeutic dosing with Tylan_ in drinking water. One publication linked tetracycline-resistant C. jejuni clone SA in raw cow’s milk to a foodborne outbreak in humans. No studies that identified farm antimicrobial use also traced antimicrobial-resistant Campylobacter from farm to fork. Recent literature confirms that on farm antibiotic selection pressure can increase colonization of animals with drug-resistant Campylobacter spp. but is inadequately detailed to establish a causal relationship between use of antimicrobials in agricultural animals and prevalence of drug-resistant foodborne campylobacteriosis in humans.

Source: AASV

Video: Heat Stress in Pigs: What to Prepare for Before Next Summer - Dr. Joshua Selsby

In this episode of The Swine it Podcast Show Canada, Dr. Joshua Selsby from Iowa State University explains how heat stress affects swine biology and why now is the ideal time to prepare for next summer’s challenges. He breaks down its effects on muscle function, immune responses, and long-term metabolic outcomes. Learn how early planning can protect herd performance when temperatures rise again. Listen now on all major platforms! "Heat stress leads to a cascade of biological damage, beginning with metabolic disruption and expanding across multiple organ systems." Meet the guest: Dr. Joshua Selsby is a Professor in the Department of Animal Science at Iowa State University. With over 15 years of research on skeletal muscle physiology and heat stress, he focuses on understanding how thermal stress disrupts swine metabolism, immune function, and muscle integrity.