Abstract: African Swine Fever Control and Prevention: An Update on Vaccine Development

Aug 05, 2022

African swine fever (ASF) is a lethal and highly contagious viral disease of domestic and wild pigs, listed as a notifiable disease reported to the World Organization for Animal Health (OIE). Despite its limited host range and absent zoonotic potential, the socio-economic and environmental impact of ASF is very high, representing a serious threat to the global swine industry and the many stakeholders involved. Currently, only control and eradication measures based mainly on early detection and strict stamping-out policies are available, however, the rapid spread of the disease in new countries, and in new regions in countries already affected, show these strategies to be lacking. In this review, we discuss approaches to ASF vaccinology, with emphasis on the advances made over the last decade, including the development of virulence-associated gene deleted strains such as the very promising ASFV-G-ΔI177L/ΔLVR, that replicates efficiently in a stable porcine epithelial cell line, and the cross-protecting BA71ΔCD2 capable of stably growing in the commercial COS-1 cell line, or the naturally attenuated Lv17/WB/Rie1 which shows solid protection in wild boar.

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Video: Shearing Delay Leads To Kingston 4H Sheep Show!

What started as a disappointment turned into a day full of surprises, fun, and celebration as we leave Ewetopia Farms behind and head out to the Kingston Fair to watch the 4H sheep show

Today’s vlog was supposed to be another sheep shearing day here at Ewetopia Farms, but when our shearer had to cancel, we suddenly found ourselves with an unexpected free day. Lucky for us, the Kingston Fair was happening — and some of our own sheep (and friends) were competing!

We brought along our shearing helper and headed to the fairgrounds to cheer on the 4H kids and see how our sheep did in the show. From last-minute preparations and sheep showmanship to market lamb competitions and ewe classes, we take you behind the scenes of what it’s really like at a country fair.

We couldn’t be prouder — our girls walked away with wins in both showmanship and breeding ewe classes! Afterwards, we toured the fair, met a beekeeper with fascinating insights, admired other livestock shows, and wrapped up the evening with motocross stunts and a demolition derby!

Sometimes farm life throws curveballs — but today, it gave us the chance to celebrate community, our sheep, and the next generation of shepherds.