Abstract: African Swine Fever Control and Prevention: An Update on Vaccine Development

Aug 05, 2022

African swine fever (ASF) is a lethal and highly contagious viral disease of domestic and wild pigs, listed as a notifiable disease reported to the World Organization for Animal Health (OIE). Despite its limited host range and absent zoonotic potential, the socio-economic and environmental impact of ASF is very high, representing a serious threat to the global swine industry and the many stakeholders involved. Currently, only control and eradication measures based mainly on early detection and strict stamping-out policies are available, however, the rapid spread of the disease in new countries, and in new regions in countries already affected, show these strategies to be lacking. In this review, we discuss approaches to ASF vaccinology, with emphasis on the advances made over the last decade, including the development of virulence-associated gene deleted strains such as the very promising ASFV-G-ΔI177L/ΔLVR, that replicates efficiently in a stable porcine epithelial cell line, and the cross-protecting BA71ΔCD2 capable of stably growing in the commercial COS-1 cell line, or the naturally attenuated Lv17/WB/Rie1 which shows solid protection in wild boar.

Click here to see more...

Video: Inside the National Swine Health Strategy - Dr. Dustin Oedekoven

In this episode of The Swine it Podcast Show, Dr. Dustin Oedekoven, Chief Veterinarian at the National Pork Board, explains the producer-led National Swine Health Strategy and why it is essential for improving U.S. swine health. He discussed industry collaboration, the strategy's initial priorities, why PEDV is the first focus for elimination, research initiatives, and the long-term vision for healthier herds. Listen now on all major platforms.

"The National Swine Health Strategy creates a coordinated approach that moves the entire industry toward common health goals."

Meet the guest: Dr. Dustin Oedekoven / dusty-oedekoven-bb0bb7110 is Chief Veterinarian at the National Pork Board, where he leads initiatives to strengthen U.S. swine health through disease prevention, producer collaboration, and the National Swine Health Strategy. With more than 20 years of experience in veterinary public health and regulatory animal health, his work focuses on protecting the U.S. herd from endemic and foreign animal diseases. Listen to Dr. Dustin Oedekoven on The Swine it Podcast Show, available on all major platforms.