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Intrauterine Vaccination of Sows and Gilts Offers Piglets Up-Front Disease Protection

An Associate Professor with the University of Saskatchewan’s College of Pharmacy and Nutrition says administration of vaccines to sows and gilts during artificial insemination offers their piglets earlier disease protection. Researchers with the Vaccine and Infectious Disease Organization and the College of Pharmacy and Nutrition at the University of Saskatchewan are evaluating the effectiveness of administering vaccines to sows and gilts along with sperm during artificial insemination to protect them and their offspring from diseases, focusing initially on Porcine Epidemic Diarrhea. Dr. Azita Haddadi, an Associate Professor with the Division of Pharmacy in the College of Pharmacy & Nutrition, says this approach offers a host of advantages.

Clip-Dr. Azita Haddadi-University of Saskatchewan:
First of all, it’s needle-free so that is one advantage. Then, in the pig industry, the majority of the commercial pigs are bred by artificial insemination so this vaccine is administered at the same time so you don’t need extra steps or extra procedures.
The other advantage is, because it’s in the uterus, it could cause some immunity in the mucus of the uterus that will better protect the fetus and, when the piglets are born, they’re already immunized. The first six weeks after the birth is the most challenging time for the piglets because their immune system is not fully developed yet and they have a higher chance of getting infected.
With this method when they’re born, they already have the immunization.

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In this episode of The Swine it Podcast Show, Dr. Neil DeBuse from Kalmbach Feeds and Dr. Steve Tousignant from Vaxxinova US discuss PRRS management strategies, recombination risks, whole genome sequencing, and the role of autogenous immunization programs in swine systems. They highlight practical approaches to improving immunity, reducing outbreaks, and advancing PRRS control across production systems. Listen now on all major platforms!

"Being PRRS negative sooner is a real key for eradication because every additional positive week increases production losses and viral exposure risks." - Dr. Neil DeBuse

Meet the guest: Dr. Neil DeBuse is a veterinarian at Kalmbach Feeds with more than 30 years of experience in swine health and production. His work focuses on PRRS control, biosecurity, immunity, and improving production stability across commercial swine systems in the United States and internationally.

Dr. Steve Tousignant is Director of the Swine Business Unit and Technical Services Veterinarian at Vaxxinova US, with a DVM and PhD from the University of Minnesota. His experience combines epidemiology, technical services, and practical immunization strategies designed to support consistent herd performance and long-term production stability. Don’t miss the chance to be part of the Swine Inner Circle!