NASDBPP Releases Findings

Hypothesis: If PCR+ spray-dried porcine plasma contains infective PEDv and is a vector spreading PED:

Then:

Results of controlled experiments:

1: PEDv will survive spray drying.

1: Spray drying inactivated PEDv.

2: Retained samples of plasma investigated by CFIA in bioassay will contain infective PEDv.

2: Retained plasma samples subjected to bioassay studies by FDA and NASDBPP were not infective for PEDv.

3: Nursery feed containing PEDv PCR+ plasma should infect pigs.

3: Two independent studies using 21-day-old weaned pigs fed 5% PEDv PCR+ plasma in a meal diet for 21 or 28 days post-weaning did not infect pigs with PEDv.

4: Spray-dried plasma contaminated post-processing with PEDv should survive through distribution until consumed by pigs.

4: PEDv inoculated on spray-dried plasma did not survive by: 7 days stored at 71°F (22°C) 14 days stored at 54°F (12°C) 21 days stored at 39°F (4°C)

5: Pigs in a PEDv-free region fed PEDv PCR+ plasma from the US should become infected with PEDv.

5: Millions of pigs in Brazil and Western Canada fed PEDv PCR+ porcine plasma imported from the US since last summer have not developed PEDv.

Conclusion: 
• Experimental results show that PCR+ spray-dried porcine plasma does not contain infective PEDv. 
• Infective PEDv reported by CFIA on samples of spray-dried porcine plasma collected from the field is likely the result of post-processing contamination.