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Vaccination Can Strategically Support The Protection Of Poultry Against Highly Pathogenic Avian Influenza

Vaccination Can Strategically Support The Protection Of Poultry Against Highly Pathogenic Avian Influenza

By Friedrich-Loeffler-Institut

The highly pathogenic avian influenza virus (HPAIV) of the subtype H5 has progressed from sporadic seasonal occurrences to a continuous and nearly global panzootic in wild birds. This raises HPAIV incursion pressure into poultry holdings, as well as the risks of secondary spread and human exposure at the poultry-human interface.

A group of international scientists has outlined how vaccination with zero-tolerance for infection can be achieved by usefully supplementing multiple layers of appropriate surveillance. The scientists from Germany, the Netherlands, Italy, Indonesia and Hong Kong have presented their finding in the most recent issue of Biologicals.

Recent developments toward a massively increased circulation of HPAIV in  and in the  in many regions across the world have moved vaccination into focus as a complementary prevention tool in major parts of the globe. HPAI vaccination has never been successful in controlling HPAIV on its own. Biosecurity, continuous evaluation of vaccination uptake and efficacy, adequate surveillance of vaccinated flocks to ensure the freedom from field infections, and typing of detected field strains to improve  are all equally required.

Vaccination as an additional layer of protection of poultry holdings using appropriately matched vaccines aims at reducing clinical sequelae of HPAIV infection, disrupting HPAIV transmission, curtailing  and animal welfare problems and cutting exposure risks of zoonotic HPAIV at the avian-human interface.

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