HRAC approves first dual action herbicide to fight resistant weeds
FMC Corporation has announced an advancement in crop protection with the classification of rimisoxafen as the first dual mode of action of herbicide by the Herbicide Resistance Action Committee (HRAC). This decision marks an important moment for the global agriculture industry and highlights new progress in the fight against herbicide resistant weeds.
Rimisoxafen works by targeting two important biochemical pathways in weeds. It blocks both phytoene desaturase (PDS) and solanesyl diphosphate synthase (SDPS), making it harder for weeds to survive or develop resistance. This dual action creates a stronger and more reliable weed control system compared to traditional single mode herbicides.
According to FMC, the herbicide has shown strong results against problematic weeds such as palmer amaranth and waterhemp. These weeds have become increasingly difficult to control as they develop resistance to several herbicide groups. Palmer amaranth, for example, has shown resistance to multiple herbicide modes, creating serious challenges for farmers.
The new technology is designed mainly for broadacre crops, including corn, soybean, cereals, pulses and sunflower. By improving weed management, rimisoxafen could help growers protect yields and reduce production risks caused by resistant weeds.
FMC scientists discovered the molecule at the company’s Stine Research Center. The company says rimisoxafen is the third new herbicide it has developed for regulatory submission in recent years, following earlier innovations such as Isoflex® active and Dodhylex™ active.
"HRAC's historic classification of rimisoxafen validates the breakthrough nature of this technology," said Seva Rostovtsev, executive vice president and chief technology officer. "Studies show this molecule delivers control of palmer amaranth and waterhemp, giving farmers an effective solution against weeds that have become resistant to multiple herbicide classes. This is the kind of innovation growers need to protect their crops and their livelihoods."
FMC expects to begin regulatory submissions for rimisoxafen in key markets starting in 2026. This step will move the product closer to commercial use and provide growers with an additional tool for long-term resistance management.
Overall, the dual mode of action classification represents a significant development for modern agriculture. It reflects the growing need for innovative solutions that help farmers manage evolving weed challenges while maintaining sustainable crop production systems.
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