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Pangenome Unlocks Potential of Barley's Closest Wild Relative

Wild plants can contribute valuable genes to their domesticated relatives. Fertility barriers and a lack of genomic resources have hindered the effective use of crop-wild introgressions. An international research team led by the IPK Leibniz Institute constructed a pangenome of barley's closest wild relative, Hordeum bulbosum. The study is published today in the journal Nature.

Wild relatives of cultivated plants are a vital source of genetic diversity for improving crops and provide a valuable reservoir of resistance against biotic and abiotic stressors. Although their value has been recognized for decades, technological obstacles have long hindered their exploration. Thanks to advances in high-throughput genomic research, the same tools can now be used in crops and their wild relatives.

An international research team led by the IPK Leibniz Institute studied structural genome evolution in barley (Hordeum vulgare) and Hordeum bulbosum. For this study, Dr. Frank Blattner collected H. bulbosum genotypes in  all over the Mediterranean, which, combined with accessions from genebanks, resulted in a panel of 263 diverse genotypes. This collection comprises both diploid and tetraploid cytotypes. After analyzing their , the research team assembled and annotated ten reference-quality chromosome-scale genomes of bulbous barleys.

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Democratizing Gene Editing - Pairwise’s Vision for the Future of Agriculture

Video: Democratizing Gene Editing - Pairwise’s Vision for the Future of Agriculture

Pairwise has built its business around an idea that runs counter to how many companies approach innovation: make transformative technology easier to access.

In this Seed World interview, CEO Tom Adams discusses why broader access to gene editing could speed crop improvement, expand innovation opportunities and help agriculture address emerging challenges. He explains why Pairwise believes no single company can solve all of agriculture's problems alone—and why making advanced breeding technologies available to more organizations could accelerate progress across the industry.

The conversation explores how consumer trust influences technology adoption, why innovations like pitless cherries and seedless blackberries matter beyond convenience, and how future crop improvements could help address labor shortages, automation, harvest efficiency and other production challenges. Adams also shares his perspective on what the industry may be underestimating about the next wave of gene editing innovation.

Watch the full interview to hear why Pairwise believes agriculture is approaching an important inflection point for gene editing, and why the pace of innovation over the next decade could surprise the industry.

Topics Covered:

o Democratizing agricultural innovation

o Consumer trust and technology adoption

o The business case for sharing innovation

o Expanding innovation beyond major crops

o Next-generation breeding technologies