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Abstract: Japanese Encephalitis Virus: an Emerging Threat

Japanese encephalitis (JE) is an infection that occurs predominantly in Asia and the Pacific Islands. It is transmitted by mosquito bites, with the main vector being Culex tritaeniorhynchus, and is maintained in enzootic cycles involving pigs, wild birds and mosquitoes. JE is caused by infection with Japanese encephalitis virus (JEV), a zoonotic pathogen that also causes disease in mammals such as pigs and horses. In humans, most symptoms are mild or flu-like but can progress to encephalitis. Pigs are considered amplification hosts, and sows may have gestational complications. Horses may exhibit neurological signs. Detection of the virus can be confirmed by serological or molecular laboratory tests. 

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Four Star Pork Industry Conf - Back to Basics: Fundamentals drive vaccine performance

Video: Four Star Pork Industry Conf - Back to Basics: Fundamentals drive vaccine performance

At a time when disease pressure continues to challenge pork production systems across the United States, vaccination remains one of the most valuable and heavily debated tools available to veterinarians and producers.

Speaking at the 2025 Four Star Pork Industry Conference in Muncie, Indiana, Dr. Daniel Gascho, veterinarian at Four Star Veterinary Service, encouraged the industry to return to fundamentals in how vaccines are selected, handled and administered across sow farms, gilt development units and grow-finish operations.

Gascho acknowledged at the outset that vaccination can quickly become a technical and sometimes tedious topic. But he said that real-world execution, not complex immunology, is where most vaccine failures occur.