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Horse Dies of West Nile in First Known Case of ’23

A 13-year-old gelding in Dillon County, South Carolina, died from the first confirmed West Nile Virus (WNV) case of the year, according to State Veterinarian Michael J. Neault, director of Clemson Livestock Poultry Health.

The diagnosis was made during necropsy and confirmed by the National Veterinary Services Laboratories Sept.13. The horse’s vaccination status is unknown.

A total of six horses have died from preventable mosquito borne diseases in 2023. In addition to the most recent death from WNV, horses in Sumter, Lee, Berkeley, Kershaw and Dillion counties have died from Eastern Equine Encephalitis (EEE).

While horse owners can take measures such as turning them in at dawn and dusk and using spray repellents, vaccination is the only surefire way to protect their horses from EEE, WNV and rabies.

“Horse owners must stay on top of equine vaccination schedules in order to protect their horses from these diseases,” Neault said.

Borne by mosquitoes, these diseases have a very high mortality rate in infected, unvaccinated horses — between 30 and 40 percent for WNV and 90 percent for EEE. However, widespread vaccination has kept the number of cases comparatively low in South Carolina compared to nearby states.

Likewise, mosquito control is an important precaution. Both EEE and WNV are maintained in nature through a cycle involving the freshwater swamp mosquito, Culiseta melanura, commonly known as the black-tailed mosquito.

The EEE and WNV viruses are fast-acting. Symptoms of both diseases usually develop from two to five days after exposure and include neurologic difficulties such as stumbling, circling, head pressing, depression or apprehension, weakness of legs, partial paralysis, the inability to stand, muscle twitching or death.

Source : clemson.edu

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Leman Swine Conference: Vaccination strategies to reduce PRRS virus recombination

Video: Leman Swine Conference: Vaccination strategies to reduce PRRS virus recombination

Dr. Jay Calvert, Research Director with Zoetis, recently spoke to The Pig Site’s Sarah Mikesell at the 2023 Leman Swine Conference in St. Paul, Minnesota, USA, about his conference presentation on porcine reproductive and respiratory syndrome (PRRS) virus recombination.

“The number one problem in PRRS these days from a vaccine point of view is the emergence of new strains of PRRS. Since the beginning, we have had new strains and a lot of diversity,” said Dr. Jay Calvert. “We thought we knew it was all about mutation changes in amino acids and the individual strains over time, but they take on new characteristics.”

With the onset of more common whole genome sequencing and recombination analysis, Dr. Calvert says there is another mechanism, and recombination seems to be a key factor.