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Research aims to help with boar heat stress

In utero heat stress of boars is a significant threat to pork production, and a University of Nebraska reproductive physiologist is leading a research team that aims to develop boars that are more genetically tolerant of gestational heat stress.

In the United States, about 6 million sows a year produce a litter after exposure to gestational heat stress, a threat that is increasing with climate change. At an average of 11 animals in a litter, that’s 66 million piglets affected each year in the U.S. alone, according to a university news release.

Researchers have known for decades that direct exposure to summer heat stress dramatically impairs sperm production in adult males. In addition, new evidence demonstrates that exposure to in utero heat stress, or IUHS, also impairs boar sperm production, decreasing counts by about 24% and increasing the proportion of abnormal sperm by about 42%. That renders the semen poor quality, said Amy Desaulniers, assistant professor of veterinary medicine and biomedical sciences and the project’s principal investigator.

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Porcine Gut Models in Nutrition Research - Dr. Li-Hsuan Chen

Video: Porcine Gut Models in Nutrition Research - Dr. Li-Hsuan Chen



In this episode of The Swine Nutrition Blackbelt Podcast, Dr. Li-Hsuan Chen, postdoc researcher at Aarhus University, discusses how porcine intestinal cell lines and organoids can help study the impact of nutrition on gut health. He explains how in vivo piglet trials identify diet-driven shifts in microbiota and metabolites, while in vitro models allow researchers to test specific metabolites, barrier function, immune markers, and future organ-on-chip systems before moving back to animal studies. Listen now on all major platforms!

"In vitro models can reduce early animal use by helping researchers screen nutritional candidates before moving back to in vivo trials."

Meet the guest: Dr. Li-Hsuan Chen / li-hsuan-chen-9a95a7279 is a postdoc researcher at Aarhus University in Denmark. Research focuses on porcine gut health, host-microbe interactions, cell lines, and organoids, with PhD work at Aarhus University studying how dietary protein and amino acid levels shape gut microbiota, microbial metabolites, and intestinal epithelial responses. Learn more from Dr. Li-Hsuan Chen on The Swine Nutrition Blackbelt Podcast, available on all major platforms.