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Researchers Explore Potential of Using Yeast in Feed to Displace Antibiotics

Researchers with VIDO are exploring the potential of using modified brewer's yeast in place of antibiotics in the rations of young piglets.Researchers with the Vaccine and Infectious Disease Organization in partnership with Renaissance Bioscience with funding provided by the Saskatchewan Agriculture Development Fund are exploring the potential of using yeast to deliver antimicrobial peptides and essential amino acids to the gut of the pig.

Dr. Heather Wilson, a Research Scientist with VIDO and an Adjunct Professor in the Department of Veterinary Microbiology and the School of Public Health at the University of Saskatchewan, says the goal is to develop feed supplements that will attack bacteria and viruses in the gut without the risk of antimicrobial resistance.

Quote-Dr. Heather Wilson-Vaccine and Infectious Disease Organization:

Yeast is already used as a feed supplement so what we're doing is using the yeast as a feed supplement but we're also putting in a protein on the surface of the yeast so that the yeast, once it travels from the mouth to the stomach to the small intestine, it will attach itself to the wall of the small intestine.
It'll stay there for a couple of hours and it'll eventually be degraded but, in the meantime, it's localised to the small intestine and then it will secrete these antimicrobial peptides which we hope will improve piglet health, keep them nice and healthy, especially during the stressful time when piglets are going from having mother's milk to weaning.

It tends to be a very stressful time for pigs so if we can give them a little something extra to help their intestines to remain healthy it can increase their growth which will eventually lead to their better wellbeing and hopefully they'll gain weight faster and so it'll be better for the producers as well.

Dr. Wilson notes this work is in its early days and will take a few years to yield results.To learn more about this work email heather.wilson@usask.ca.
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Source : Farmscape.ca

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Sweetener Effects on Gut Health - Dr. Kwangwook Kim

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In this episode of The Swine Nutrition Blackbelt Podcast, Dr. Kwangwook Kim, Assistant Professor at Michigan State University, discusses the use of non-nutritive sweeteners in nursery pig diets. He explains how sucralose and neotame influence feed intake, gut health, metabolism, and the frequency of diarrhea compared to antibiotics. The conversation highlights mechanisms beyond palatability, including hormone signaling and nutrient transport. Listen now on all major platforms!

“Receptors responsible for sweet taste are present not only in the mouth but also along the intestinal tract.”

Meet the guest: Dr. Kwangwook Kim / kwangwook-kim is an Assistant Professor at Michigan State University, specializing in swine nutrition and feed additives under disease challenge models. He earned his M.S. and Ph.D. in Animal Sciences from the University of California, Davis, where he focused on intestinal health and metabolic responses in pigs. His research evaluates alternatives to antibiotics, targeting gut health and performance in nursery pigs.