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Scientists in Africa Use Gene Editing to Protect Crops from Local Threats

In a race against a devastating parasite, African researchers are pioneering using CRISPR to improve local crops. Led by scientists like Steven Runo of Kenya, these efforts tackle challenges like witchweed infestations in sorghum and lethal diseases in maize, with promising results.

Sorghum, a staple food and versatile crop, suffers greatly from Striga, a parasitic weed siphoning off nutrients and crippling yields. Runo's team, though not the first to field-test gene-edited crops in Africa, is working on sorghum resistant to this threat. Their CRISPR-edited variety mimics natural mutations in resilient wild strains, offering hope for future field trials.

The innovation doesn't stop there. Kevin Pixley's team works on various fronts, from tackling maize diseases to making pearl millet flour last longer and boosting groundnut resistance to a cancer-causing fungus. Even livestock benefits, with projects like Dan Carlson's heat- and disease-tolerant cattle edits.

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Democratizing Gene Editing - Pairwise’s Vision for the Future of Agriculture

Video: Democratizing Gene Editing - Pairwise’s Vision for the Future of Agriculture

Pairwise has built its business around an idea that runs counter to how many companies approach innovation: make transformative technology easier to access.

In this Seed World interview, CEO Tom Adams discusses why broader access to gene editing could speed crop improvement, expand innovation opportunities and help agriculture address emerging challenges. He explains why Pairwise believes no single company can solve all of agriculture's problems alone—and why making advanced breeding technologies available to more organizations could accelerate progress across the industry.

The conversation explores how consumer trust influences technology adoption, why innovations like pitless cherries and seedless blackberries matter beyond convenience, and how future crop improvements could help address labor shortages, automation, harvest efficiency and other production challenges. Adams also shares his perspective on what the industry may be underestimating about the next wave of gene editing innovation.

Watch the full interview to hear why Pairwise believes agriculture is approaching an important inflection point for gene editing, and why the pace of innovation over the next decade could surprise the industry.

Topics Covered:

o Democratizing agricultural innovation

o Consumer trust and technology adoption

o The business case for sharing innovation

o Expanding innovation beyond major crops

o Next-generation breeding technologies