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Huskers aim to crack code of major swine virus

Two University of Nebraska-Lincoln scientists have received a $627,000 federal grant to study a viral disease posing a significant threat to the swine industry worldwide. 

Porcine reproductive and respiratory syndrome virus is widespread, causing reproductive failure in sows and major respiratory illness in pigs of all ages. In addition, the virus modulates the pig’s immune system, making the animal more susceptible to other infectious diseases. The costs to the U.S. swine sector from PRRSV annually total an estimated $1.1 billion. 

Hiep Vu, associate professor of animal science, is the co-director of the research project, funded by a three-year grant from the U.S. Department of Agriculture. The other co-director is Sarah Sillman, assistant professor with Nebraska’s School of Veterinary Medicine and Biomedical Sciences and the Nebraska Veterinary Diagnostic Center. 

The project will examine how PRRSV infects swine macrophages, the immune cells that recognize, engulf and destroy harmful intruders, including viruses and bacteria. 

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Inside the Swine Disease Reporting System - Dr. Guilherme Cezar

Video: Inside the Swine Disease Reporting System - Dr. Guilherme Cezar

In this episode of The Swine it Podcast Show Canada, Dr. Guilherme Cezar from Iowa State University explains how the Swine Disease Reporting System (SDRS) tracks emerging disease trends in the U.S. swine industry. He outlines patterns in pathogen activity, including positive developments with Mycoplasma hyopneumoniae and concerning surges in PRRS variants. Gain insights into disease surveillance, biosecurity, and cross-border collaboration potential. Listen now on all major platforms!

"The Swine Disease Reporting System aggregates diagnostic lab data to monitor and interpret trends in nine major swine pathogens."

Meet the guest: Dr. Guilherme Cezar / guilhermec-veterinario-037064168 is a veterinarian and Ph.D. candidate in Veterinary Preventive Medicine at Iowa State University, where he also serves as the Coordinator of the Swine Disease Reporting System (SDRS). With a strong background in swine health, biotechnology, and field epidemiology, he focuses on infectious disease trends and data-driven solutions.